Stereochemistry ABSOLUTE
Sub-atomic Formula C16H30O
Sub-atomic Weight 238.4094
Optical Activity UNSPECIFIED
Characterized Stereocenters 1/1
E/Z Centers 0
Charge 0
Construction of MUSCONE
Trade Data
Structure Search
Muscone is the key flavor part of musk that is quite possibly the most famous normal scent. Muscone is a promising specialist for treating intervertebral circle degeneration through its calming impacts. Musk disseminating into the mind through blood cerebrum hindrance gives the premise with its impact in treating cerebrum problems. Muscone might be a little dynamic atom with neuroprotective properties, and that restraint of apoptosis and Fas is a significant instrument of neuroprotection by muscone. These discoveries recommend an expected restorative job for muscone in the treatment of stroke. Muscone has a defensive impact against ischemia-reperfusion injury in cardiovascular myocytes, demonstrating that muscone may possibly give remedial advantage in ischemia-reperfusion injury by restraining cell oxidative pressure and apoptosis.
CNS Active3,656
Ruzicka, L.1
Unknown116,683
Targets
Conditions
Essential Target Pharmacology Condition Potency
Apoptosis144
Inhibitor7,701 Myocardial infarctionStroke
Oxidative Stress149
Inhibitor7,701 Myocardial localized necrosis
Fas flagging pathway1
Inhibitor7,701 Stroke
PubMed
Licenses
Show
5
passages
Search…
Title Date PubMed
Blends of macrocyclic items with a musky scent; new union of muscone.
1947 Dec 1
18897227
Blend of (R)- and (S)- muscone.
2002 Jun
12162565
Mental impacts of musky mixtures: examination of androstadienone with androstenol and muscone.
2002 Nov
12460587
Enlistment of cytochrome P450 3A by Shexiang Baoxin L-muscone Pill and its fundamental parts.
2012 Jan 25
22178124
Showing 1 to 4 of 4 entriesPrevious1Next
In Vivo Use Guide
150 mg/kg for 3 days
Course of Administration: Intraperitoneal
In Vitro Use Guide
In end-plate chondrocytes, exogenous IL-1b brought about an increment of endogenous IL-1b, TNF-a, and COX-2 mRNA articulation, however treatment with 25 uM/L muscone diminished the three cytokines initiated by exogenous IL-1b. In end-plate chondrocytes, nitrite levels were incited by IL-1b. The reaction was lessened by muscone in a portion subordinate way, particularly by 25 uM/L muscone.
Show
5
passages
Search…
Name Type Language
MUSCONE
Normal Name English
MUSCONE [INCI]
Normal Name English
(-)-3-METHYLCYCLOPENTADECANONE
Efficient Name English
MUSCONE [MI]
Normal Name English
CYCLOPENTADECANONE, 3-METHYL-, (3R)-
Efficient Name English
Showing 1 to 5 of 6 entriesPrevious12Next
Show
5
passages
Search…
Code System Code Type Description
FDA UNII
UPS3C6CV36 PRIMARY
WIKIPEDIA
Muscone PRIMARY
RXCUI
1606471 PRIMARY RxNorm
CAS
10403-00-6 PRIMARY
PUBCHEM
7160826 PRIMARY
Showing 1 to 5 of 6 entriesPrevious12Next
SUBSTANCE RECORD
UPS3C6CV36
Construction of MUSCONE
MUSCONE